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Acid-Base Balance Tutorial

by "Grog" (Alan W. Grogono), Professor Emeritus, Tulane University Department of Anesthesiology

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Acid-Base Diagram:

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Acid-Base Diagram Icon"Pruning a rose or building a sandcastle might seem like common activities, but when you see them visualized on paper in wordless, step-by-step diagrams, you'll discover them anew." – About Wordless Diagrams by Nigel Holmes 2005.
Acid-Base Balance Diagram: All the Typical Zones
Acid-Base Balance Diagram: All the Typical Zones

Acid-Base Balance Diagram: All the Typical Zones


The Acid-Base Diagram presented here is based on a paper written by Schlichtig R, Grogono AW., and Severinghaus JW. The paper summarized data collected by Dr. Schlichtig from 21 published reports of typical acid-base disturbances. The red and blue zones on the diagram on the right (click to enlarge) are based on the regression slopes derived from his comprehensive collection of data. Each zone accurately represents the group but an occasional individual will lie outside the zone: examine the patient as well!

The two axes are the Respiratory Component (PCO2) and the Metabolic Component – Standard Base Excess (SBE). The pH and Bicarbonate lines are also displayed on the diagram. Bicarbonate values clearly measure neither the Respiratory Component nor the Metabolic Component.

Interactive Diagram Page:

The Large Teaching version allows you to explore the diagram and experiment. This version of the diagram will also resize itself to fill the window.

Other Diagram Pages:

You can also enter your Own Data, view Selected Examples, and Test Yourself.

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Acid-Base Tutorial
Alan W. Grogono
Small Logo Copyright Mar 2018.
All Rights Reserved
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